Chen Lab's Research

Our research focuses on 3D bioprinting and biomaterials for tissue engineering and regenerative medicine applications. We explore new knowledge of cell-material interactions in the full range of physical dimensions (from nano- to micro- to meso-scale), time span (from femtoseconds to months), and biological dimensions (from molecular to cellular to tissue). Our group not only investigates the fundamental scientific issues, such as cell interactions with micro and nano-environments, biomaterials science, and biomechanics, but also solves the technological and translational issues associated with tissue/organ repair and regeneration.

Press and interviews about our work have appeared in NIH Director’s Blog, NIH Research Matters, NSF News, The Washington Post, The Wall Street Journal, Forbes, EurekAlert!, The Economic Times, Yahoo News, CNBC News, ABC News, etc. Our research has resulted in many patents/provisional patents. Some of them were licensed to companies (e.g. Allegro 3D, Inc.) with significant economic impact.

Specific Research Topics are:
1. 3D Printing and Bioprinting
2. Stem Cells and Tissue Engineering
3. Biomaterials and Nanomaterials
4. Organ/Tissue-on-a-Chip

Group Highlights

Dr. Shaochen Chen

Dr. Chen

Professor and Chair of NanoEngineering Department, UCSD


  • Dr. Chen received "Teacher of the Year" Award from the Jacobs School of Engineering at UCSD, 2019. This award is given to the Best Undergraduate Instructor in the NanoEngineering Department.
  • UC TV highlighted our 3D bioprinting and stem cell work.
  • Our work on "Biomimetic 3D-Printed Scaffolds for Spinal Cord Injury" is now published in Nature Medicine. This work was also reported by NIH Director's Blog in June 2019.
  • Jacob Schimelman received the prestigious NSF graduate fellowship. (2018)
  • Michelle Ma is selected as a Siebel Scholar and selected as a finalist of Life Science Award in 3D Printing by Millipore Sigma
  • Dr. Chen received the Milton C. Shaw Manufacturing Research Medal from ASME for his "seminal contribution to the science and technology of manufacturing processes in the area of 3-D printing, bioprinting and nanomanufacturing" (6.2017)
  • Our former MS and PhD graduate, Dr. Carlos Aguilar is now Assistant Professor at the University of Michigan, Ann Arbor (

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